The Mechanochemistry of Muscular Contraction

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The Mechanochemistry of Muscular Contraction

The dependence of PC a and ATP 1 dephosphorylation on the number of isometric twitches in the iodoacetate-nitrogen-poisoned muscle has been examined. There is no net dephosphorylation of adenosinetriphosphate. PC dephosphorylation varies linearly with the number of twitches and produces equivalent amounts of C a and p~.l Iodoacetate concentrations which block the enzyme, creatine phosphokinase,...

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The Mechanochemistry of Muscular Contraction

The dependence of PC(1) and ATP(1) dephosphorylation on the number of isometric twitches in the iodoacetate-nitrogen-poisoned muscle has been examined. There is no net dephosphorylation of adenosinetriphosphate. PC dephosphorylation varies linearly with the number of twitches and produces equivalent amounts of C(1) and P(1i).(1) Iodoacetate concentrations which block the enzyme, creatine phosph...

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Kinetics of Muscular Contraction-I **

The kinetics of muscular contraction is basic for the quantitative description of muscle and understanding its molecular mechanism. However, the subject has been embarrassed by several historical accidents. First, due to the lack until recently of adequate high (mechanical) impedance transducers, attention was focussed on isotonic measurement; this led to the idea of muscle as a shortening gene...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1960

ISSN: 1540-7748,0022-1295

DOI: 10.1085/jgp.44.1.33